W. H. Sebrell and Robert S. Harris (Eds.)'s The Vitamins. Chemistry, Physiology, Pathology, Methods PDF

By W. H. Sebrell and Robert S. Harris (Eds.)

ISBN-10: 0126337632

ISBN-13: 9780126337631

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G. Verly and W. J. Cathey, /. Biol. Chem. 213, 621 (1955). 254 J. N. , /. Biol. Chem. 191, 123 (1951). 255 J. N. , /. Biol. Chem. 192, 81 (1951). 256 J. S. Dinning, C. K. Keith, P. L. Davis, and P. L. Day, Arch. Biochem. 27, 89 (1950). 246 40 6. CHOLINE the enzymes that methylate homocystine. 257 The reduction in methionine formation resulting from the feeding of aminopterin was prevented by citrovorum factor. 258 In contrast to the slight influence of a synthetic citrovorum factor, leucovorin, folic acid was necessary for the optimal formation of A^-methylnicotinamide from administered nicotinamide in rats.

The transfer of methyl to guanidoacetic acid to form creatine, however, was irreversible. 130, 131 This impressive evidence of transfer of intact methyls was given additional support by the experiment in which choline was isolated after feeding rats doubly labeled methionine. Within experimental error the same ratio of 14 C to deuterium was found in choline and creatine methyl as in the sulfur methyl of the administered methionine. , a mixture of methionine-methyl-14C and methionine-methyl-D. Subsequently it was found that deuterium labeled methyls were oxidized more slowly than those containing protium.

Boggiano, B. Smith, and B. L. Hutchings, Federation Proc. 14, 282 (1955). -E. Ericson, J. N. , and C. A. Elvehjem, J. Biol. Chem. Ill, 537 (1955). J. Durrell, D. G. Anderson, and G. L. Cantoni, Biochim. Biophys. Acta 26, 270 (1957). H. J. Fromm and R. C. Nordlie, Arch. Biochem. Biophys. 81, 363 (1959). W. A. Klee, Biochim. Biophys. Acta 45, 537 (1960). W. A. Klee and G. L. Cantoni, Biochim. Biophys. Acta 45, 545 (1960). G. A. Maw, Biochem. J. 58, 665 (1954); 63, 116 (1956). G. A. Maw, Biochem. J.

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The Vitamins. Chemistry, Physiology, Pathology, Methods by W. H. Sebrell and Robert S. Harris (Eds.)


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