Download e-book for iPad: The Sperm Cell, Production, Maturation, Fertilization, by Christopher J. De Jonge, Christopher Barratt

By Christopher J. De Jonge, Christopher Barratt

ISBN-10: 0521853974

ISBN-13: 9780521853972

Initially released in 2006, it is a accomplished and definitive account of the human male gamete. the quantity summarizes many particular and revealing features of the sperm phone. It presents an in depth assessment of human sperm construction, maturation and serve as, and appears at how those procedures have an effect on and impact fertility, infertility and artwork. the amount therefore offers a close evaluation of crucial learn and advancements, augmented with pertinent references. This booklet will attract all practitioners and scientists in reproductive medication and particularly to medical scientists, graduate and post-graduate scientists, and laboratory group of workers.

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Additional resources for The Sperm Cell, Production, Maturation, Fertilization, Regeneration

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Brewer L, Corzett M and Balhorn R (2002) Condensation of DNA by spermatid basic nuclear proteins. J Biol Chem 277, 38895–38900. Brinster RL and Avarbock MR (1994) Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci USA 91, 11303–11307. Byskov AG and Hø´yer PE (1994) Embryology of mammalian gonads and ducts. In: The Physiology of Reproduction, eds E Knobil and JD Neill, 2nd edn. New York: Raven Press Ltd, pp. 487–540. Cataldo L, Baig K, Oko R, Mastrangelo MA and Kleene KC (1996) Developmental expression, intracellular localization, and selenium content of the cysteine-rich protein associated with the mitochondrial capsules of mouse sperm.

The Donut-Loop model (Fig. 1) predicts at least three separable levels of chromatin accessibility. The first and most open is the toroid linker region that contains the nuclear MAR. , 2003). , 2004; Wykes and Krawetz, 2003a). This suggests that the toroid linkers may be in the more open histone bound configuration. The second level of accessibility would be the chromatin fibers that are on the surface of the protamine toroid (Fig. 1). 1. ) ALL (histones ϩ protamines) ALL (histones ϩ protamines) Neutral COMET Alkaline COMET be accessible to enzymes, but the protamines that bind so completely to this DNA would probably severely, if not completely, inhibit the activity of DNA binding enzymes.

After acrosomal exocytosis, the upper edge is opened from where equatorin is expelled out, while some of it remains adsorbed on the outer face of the equatorial plasma membrane (Manandhar and Toshimori, 2001). After ZP penetration, spermatozoa possess equatorin on the equatorial plasma membrane. Hence equatorin is latent in the intact spermatozoa and expressed on the equatorial membranes at the time when they are ready to interact with the oolemma. It might either directly participate in sperm–oocyte membrane fusion or modify the putative fusion molecules of the equatorial plasma membrane making them functional.

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The Sperm Cell, Production, Maturation, Fertilization, Regeneration by Christopher J. De Jonge, Christopher Barratt

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