By Dominici D., Maier R.S. (eds.)
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Additional info for Special Functions and Orthogonal Polynomials
Summary of properties of human t r a n s f e r factor to hemocyanins. 1. 2. Non-immune donors do not t r a n s f e r hemocyanin r e a c t i v i t y . TF a c t i v i t y i s only observed a f t e r immunization of donors (man or animals) to the antigen. 3. TF a c t i v i t y elutes at 2-3 V0 on Sephadex G-25 compared to a l l other fractions. 4. TF has an i s o e l e c t r i c point o f approximately 2. 5. TF a c t i v i t y i s found i n two Chromatographie regions by high pressure reverse phase chromatography.
D. = 40 yg alumina + 50 yg Ag. Immunized with Induration (mm) at 24 hrs SK-SD/alum SK-SD BSA Normal 5x5++ 4x5++ 4x5++ a BSA/alum 1x3 2x4+1x3 1x3 1x3 2x2 7x8++ 8x9++ 8x8++ 1x3+ 2x4+2x2+ 2x2+2x2+ 2x4+- 1x3 2x4+1x3 2x2+2x2+1x3 marked induration. (23) 21 THE IMMUNOLOGICAL ENIGMA OF TRANSFER FACTOR TABLE VIII. d. = 40 yg alumina + 50 yg Ag. 5K Fr. (29)y also 4X4++ 3X4++ 3X3+pp. 35,36 0X0 0X0 2X2+ibid. Left side of the table suggests strongly, by UdR uptake, that specificity of transfer is involved. The right half of the table deals, at top, with a TF D freed of 3500D diffusibles, a very welcome step, and, at bottom, with a selected fraction from a DEAE-column.
Rev. 63, 74 (1982). , J. Immunol. 126, 2148 (1981). , Immunol. Rev. 63, 5 (1982). , Molecular Immunol. 17, 591 (1980). , J. Exp. Med. 115, 914 (1982). Committee on Interferon Nomenclature, Nature (London) 286, 110 (1980). , Urban, C , and Vilöek, J. , Proc. Nati. Acad. Sci. (US) 70, 1820 (1982). , Nature (London) 296, 258 (1982). THE IMMUNOLOGICAL ENIGMA OF TRANSFER FACTOR 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123.
Special Functions and Orthogonal Polynomials by Dominici D., Maier R.S. (eds.)