By Drukker, Parsons, Maher (auth.), Walter H. Hörl, Karl M. Koch, Robert M. Lindsay, Claudio Ronco, James F. Winchester (eds.)
The major textbook at the topic. a totally rewritten and up to date 5th version, established upon the hugely revered fourth version, edited via C. Jacobs, C.M. Kjellstrand, K.M. Koch and J.F. Winchester.
Considered the worldwide source for dialysis experts, dialysis brands and scientists for over twenty years, this authoritative, hugely acclaimed significant reference paintings has been thoroughly rewritten and revised in a much-awaited fifth variation. All earlier chapters were up-to-date to incorporate the very most recent developments and understandings during this severe and complicated box. New sections comprise these on computerization of dialysis documents, on-line tracking and biofeedback, sufferer sexual functionality, sufferer choice and integration, use of workout in bettering sufferer healthiness, layout of randomized trials, and extra. This new version is actually international in scope and lines the contributions the head specialists from round the world.
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Extra info for Replacement of Renal Function by Dialysis
Mutations in NPHS2 encoding podocin are a prevalent cause of steroid-resistant nephrotic syndrome among lsraeli-Arab children. J Am Soc Nephrol. 2002; I 3:400-5. 126. Karle SM, Uetz B, Ronner V, Glaeser L, Hildebrandt F, Fuchshuber A. Novel mutations in NPHS2 detected in both familial and sporadic steroid-resistant nephrotic syndrome. 1 Am Soc Nephrol. 2002;13:388-93. 127. Schwarz K, Simons M, Reiser 1 et al. Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.
90. 91. 92. 93. 94. 95. Tripodi G. Valtorta F, Torielli L et al. Hypertensionassociated point mutations in the adducin alpha and bcta subnnits affect actin cytoskeleton and ion transport. J Clin lnvest. 1996;97:2815-22. Staessen JA, Wang JG, Brand E et al. Effects of three candidate gcnes on prcvalence and incidence ofhypertension in a Caucasian population. J Hypertens. 2001;19:1349-58. Wang JG, Stacssen JA, Tizzoni L ct al. Renal function in relation to three candidate genes. Am J Kidncy Dis. 2001:38:1158--68.
Virtually all available enzyme systems fail to function properly. In what follows, a number of examples ofinadequate key functional processes will 21 be given. This Iist is, however, not exhaustive. Na+, K +-pump inhibition (98-1 00) results in increased cellular sodium content, arterial hypertension, and plasmatic digitalis-like or ouabain-like activity (I 01 ). The mechanism for defective cation transport is multifactorial and tissue-specific ( 102). In parallel, sodium-dependent amino acid transport is also depressed.
Replacement of Renal Function by Dialysis by Drukker, Parsons, Maher (auth.), Walter H. Hörl, Karl M. Koch, Robert M. Lindsay, Claudio Ronco, James F. Winchester (eds.)