New PDF release: Immunology of Pregnancy (Medical Intelligence Unit)

By Gil Mor

ISBN-10: 0387306129

ISBN-13: 9780387306124

Reproductive Immunology is a starting to be zone in either immunology and reproductive sciences and helps us to raised comprehend a number of issues of being pregnant. Immunology of being pregnant is the 1st publication to provide a whole and recent assessment of our wisdom on the topic of the position of the immune procedure while pregnant and the interactions among the placenta and the maternal immune procedure. This new identify covers intimately the entire varied hypotheses and stories with regards to the immunology of implantation and supply a realistic procedure for the appliance of easy reproductive immunology examine to being pregnant issues comparable to preeclampsia, pre-term hard work and IUGR.

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Sample text

Gordon S. Pattern recognition receptors: Doubling up for the innate immune response. Cell 2002; lll(7):927-930. 17. Anderson KV, Bokla L, Nusslein-Volhard C. Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product. Cell 1985; 42(3):791-798. 18. Anderson KV, Jurgens G, Nusslein-Volhard C. Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product. Cell 1985; 42(3):779-789. 19.

Placenta 2004; 25(Suppl A):S3-9. 20. Carter AM. Evolution of the placenta and fetal membranes seen in the light of molecular phylogenetics. Placenta 2001; 22:800-807. 2 1 . Rockwell CI et al. H u m a n physiological adaptation to pregnancy: Inter and intraspecific perspectives. Am J H u m Biol 2003; 15:330-341. 22. Hobbs NK. Removing the vertebrate specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system. Cell 2002; 110:43-54. 23. McDade T W , Worthman C M .

Interaction of T R I P with RIP7^ Whether T L R - 3 can mediate trophoblast cell apoptosis is, as yet, unknown. ^"^'^^ Since clinical studies have shown an association between intrauterine infections and preterm labor, preeclampsia and lUGR,^'^ we hypothesize that Toll-like receptors expressed at the maternal-fetal interface may play an important role in the mechanism of pathogenesis. We predict that certain intrauterine infections during pregnancy may have either a direct or indirect effect upon trophoblast cell survival, depending upon which T L R is activated.

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Immunology of Pregnancy (Medical Intelligence Unit) by Gil Mor

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