By Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva
The remedy of gynecologic cancers at M. D. Anderson melanoma middle has a protracted heritage of multidisciplinary cooperation. Gynecologic Cancer, the 5th quantity within the M. D. Anderson melanoma Care sequence, info M. D. Anderson’s method of the care of ladies with gynecologic cancers. Written for physicians, the ebook emphasizes the daily facets of perform, minimizing wide literature assessment and techniques now not but integrated into regimen perform.
In 17 entire but concise chapters, M. D. Anderson school describe their ways to the therapy of endometrial, ovarian, and cervical cancers, in addition to preinvasive gynecologic illnesses, vaginal and vulvar cancers, uterine sarcomas, and infrequent ovarian malignancies. as well as the discussions of person ailment websites, the e-book includes chapters on prevention, pathology, imaging, fertility-sparing suggestions, caliber of existence matters, together with sexual functioning, and palliative care. each one bankruptcy encompasses a checklist of advised readings and key perform issues that spotlight an important ideas presented.
This thorough, useful quantity, such as greater than 60 photos and line drawings, is an important medical consultant for oncologists, surgeons, and all physicians concerned with the care of sufferers with gynecologic cancers.
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Extra resources for Gynecologic Cancer
Women who are obese should be counseled to lose weight to decrease their risk of endometrial cancer. ● Oral contraceptives decrease the risk of ovarian and endometrial cancer by 50% in women in the general population and are a reasonable chemopreventive agent for women at increased risk as well. ● Women with HBOC syndrome should be advised to undergo prophylactic bilateral salpingo-oophorectomy when childbearing is complete. Pathologic review of the surgical specimens should be thorough, given the increased risk of occult ovarian and fallopian tube cancers in this population.
Am J Hum Genet 1998;62:676–689. Goff BA, Mandel LS, Melancon CH, Muntz HG. Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. JAMA 2004;291:2705–2712. Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10–30. Kauff ND, Satagopan JM, Robson ME, et al. Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med 2002;346:1609–1615. Narod SA, Risch H, Moslehi R, et al. Oral contraceptives and the risk of hereditary ovarian cancer.
According to these authors, stromal invasion in an endometrial biopsy specimen was the main histologic parameter correlating with adenocarcinoma in the subsequent hysterectomy specimen. Stromal invasion is identified by the presence of desmoplastic changes, confluent glandular growth, or an extensive papillary pattern. 2 mm in diameter) to have value in predicting the presence of a biologically significant carcinoma in the uterus. Currently, these criteria are still used, despite the fact that when stromal invasion is identified in an endometrial biopsy or curettage specimen, residual adenocarcinoma is found in only 50% of the subsequent hysterectomy specimens, and when stromal invasion is not identified, adenocarcinoma is still found in 17% of the subsequent hysterectomy specimens.
Gynecologic Cancer by Patricia J. Eifel, David M. Gershenson, John J. Kavanagh, Elvio G. Silva