Download e-book for iPad: Current topics in cellular regulation by Bernard L. Horecker, Earl R. Stadtman

By Bernard L. Horecker, Earl R. Stadtman

ISBN-10: 0121528332

ISBN-13: 9780121528331

This number of papers on mobile rules covers such issues as cytomatrix and enzyme association; membrane linked approaches; the citric acid cycle; electron delivery structures; nucleotide biosynthesis; research of metabolism in equipped states; and bioengineering functions

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Biochim. Biophys. Res. Commun. 157, 937-943. 19. Arora, K. , and Pedersen, P. L. (1990). J. Biol. Chem. 265, 64816488. 20. , and Wilson, J. E. (1988). Arch. Biochem. Biophys. 267, 803-810. 21. , and Wilson, J. E. (1990). Arch. Biochem. Biophys. 276, 285-293. 22. , and Chien, J. L. (1966). Chem. Abstr. 56, 7498a. 23. Newsholme, E. , Rollerton, F. , and Taylor, K. (1968). Biochem. J. 106,193. 24. , and Pedersen, P. L. (1977). Proc. Natl. Acad. Sei. A. 74, 37353739. 25. , and Pedersen, P. L. (1980).

Neurochem. Int. 7, 379-383. 44. , Morton, D. , and Clarke, F. M. (1980). Biochem. J. 186, 99-104. 45. Clarke, F. , and Morton, D. J. (1982). Biochem. Biophys. Res. Commun. 109, 388-393. 46. Knull, H. , Bronstein, W. , and Niehaus, W. G. (1980). J. Neurochem. 34, 222-225. 47. , and Sakai, H. (1983). J. Biochem. (Tokyo) 93,1259-1269. 48. , and Pantaloni, D. (1985). Eur. J. Biochem. 150, 265-269. 49. , and Rousset, B. (1987). Arch. Biochem. Biophys. 252, 32-40. 50. Karkhoff-Schweizer, R. , and Knull, H.

Thus, it is clear that brain as well as tumor hexokinases bind to 34 KOSAKU UYEDA membranes via the N-terminal hydrophobic region. More recently, Xie and Wilson (21) demonstrated that the bound form of rat brain hexokinase is a tetramer. Differences in the kinetic properties of soluble and bound forms of hexokinase have been reviewed extensively by Purich et al. (4). Because the bound form of hexokinase has a lower K m for ATP and is less sensitive to inhibition by glucose 6-phosphate than the soluble form (22-25), the particulate enzyme has higher activity.

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