By Jeffrey D. Hosenpud, Adnan Cobanoglu, Douglas J. Norman, Albert Starr
Over the previous ten years, cardiac transplantation has advanced from an exper imental approach played in a handful of college facilities to a attainable healing modality now played in additional than one hundred fifty facilities around the globe. The complexity of the approach, the altering immunosuppressive re gimes, and the follow-up care have necessitated a multidisciplinary ap proach concerning quite a few clinical, nursing, and social sciences unique ties and subspecialties. furthermore, overall healthiness care trainees and referring physicians are more and more turning into enthusiastic about the care of the cardiac transplant recipient. This publication doesn't try to be a entire treatise on cardiac transplantation; really, we are hoping that it'll function a handbook and instruction for all well-being execs enthusiastic about cardiac trans plantation. JEFFREY D. HOSENPUD, M.D. Contents Preface v participants IX 1. Cardiac Transplantation: an outline JEFFREY D. HOSENPUD AND ALBERT STARR Immunogenetics and Immunologic Mechanisms of two. Rejection 15 DOUGLAS J. NORMAN three. clinical remedy adapted for complicated middle Failure 33 LYNNE WARNER STEVENSON four. Ventricular advice as a Bridge to Cardiac Transplantation fifty three D. GLENN PENNINGTON AND MARC T. SWARTZ Recipient choice for Cardiac Transplantation seventy one five. GEORGE A. PANTELY 6. Donor choice and administration for Cardiac Transplantation eighty five JEFFREY SWANSON AND ADNAN COBANOGLU 7. Operative suggestions and Early Postoperative Care in Cardiac Transplantation ninety five ADNAN COBANOGLU Endomyocardial Biopsy: suggestions and Interpretation of 8.
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Additional resources for Cardiac Transplantation: A Manual for Health Care Professionals
27 In cardiac transplantation, chronic rejection is manifest by accelerated atherosclerosis that develops as a result of antibody- (and possibly cellular) mediated damage of coronary artery endothelium; this reduces natural defenses against cholesterol deposition and platelet adherence and promotes vascular smooth muscle cell proliferation. Cell-mediated rejection is the most common form of rejection encountered immediately after transplantation; most patients develop one or more episodes of this after transplantation.
22. Noreen H, van der Hagen E, Segall M, et al. Renal allograft survival in patient with positive donor specific B lymphocyte crossmatches. Transplant Proc. 1983;15: 1216-1217. 23. Wilbrandt R, Tung K. ABO blood group incompatibility in human renal homotransplantation. Am J Clin Pathol. 1969;15:15-23. 24. Roy R, Terasaki PI, Chia D, Mickey M. Low kidney graft survival in Lewis negative patients after regrafting and newer matching schemes for Lewis. Transplant Proc. 1987;19:4498-4502. 25. Millis M, Busutill R.
29. Hall B, deSaxe I, Dorsch S. The cellular basis of allograft rejection in vivo. Transplantation. 1983 ;36:700--705. 3 Medical Therapy Tailored for Advanced Heart Failure LYNNE WARNER STEVENSON The success of transplantation has encouraged referrals to transplant centers, where the supply of donor hearts is so limited that most patients cannot undergo transplantation, and those who are accepted frequently have long waiting periods. 2 The concentration of uniquely compromised patients at these centers has led to the development of therapy specifically tailored for advanced heart failure.
Cardiac Transplantation: A Manual for Health Care Professionals by Jeffrey D. Hosenpud, Adnan Cobanoglu, Douglas J. Norman, Albert Starr